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Programme: PARTNERSHIPS IN PRIORITY AREAS Project: PNCD II-P4-6. Biotechnologies; Contract: 61-001/2007 Project title: "Innovative technologies of preserving and using of probiotic lactic bacteria with superior performance to increase food security." Acronym: INCTEC Project Director: Dr. Ing. Alexandrina TOMA, Researcher Project period:36 months (2007-2010)
General objectives: - Increase knowledge competitiveness the research by completing a partnership in biotechnology food, which will contribute to obtaining and application on the level pilot / manufacturing of innovative technologies for the manufacture of dairy products functional category (food-drug). - Development of new biotechnology techniques and procedures for the preservation and use of probiotic lactic bacteria, with impact on food safety and quality of life (prevention of cardiovascular and gastrointestinal diseases) - Achievement of biological preparations with superior performance in terms of development and functional range of probiotic dairy products, for the benefit of human health - The transfer of research results of a trader in order recovery in production Project summary: Enhancing the quality of life is a desideratum of major importance in the current stage of development of Romanian society, determined by default and ensuring health of the population. One of the factors influencing the maintenance of health is the nutrition balanced in nutrients and functional ingredients with positive impact on physical or mental performance of the consumer. Awareness of the impact of this concept among the population gave birth to the emergence and development of new types of food entitled generic "functional foods". They are located on the border between conventional foods and the type of medicine and food status of benefit to human health and the prevention illness. Functional foods present a special function when ingested, are involved in regulating certain metabolic functions, such as: improving the biological mechanisms of defense (immune system), prevention of specific diseases and physiological modulation systems, the recovery after the disease control physical condition and mental, slow the aging process, etc.. Theme project aims to increase safety in use and increase the duration of manifestation of functional properties of probiotic lactic bacteria, using innovative techniques protection by microencapsulation. Encapsulating bacteria of the genus "bifidus" will be used in probiotic formula, which will be used for the biological development of a new range of probiotic dairy products. The research aim of finding solutions to increase the functional nature of lactic bacteria by protect them using special microencapsulation, so they preserve more properties. Their functional role will be demonstrated by tests „in vitro” and „in vivo”. The obtained bio-mix products will be a medicine-food with highly increased therapeutically qualities compared to the existing probiotics. The advantage of these products is that the survival rate of probiotic bacteria on the intestinal wall will be highly increased, having the guaranty of their proven therapeutic effects. Subscribed to the “BIOTECHNOLIES” research theme, the project serves the purpose of creating new technologies of obtaining biomixes containing probiotic microflora with superior biotechnological and functional qualities, and with a high safety rate for human usage. It is stipulated the extension of work from lab-level to industrial production, for developing the range of functional products with superior properties and a high rate of food safety. Products made in the research works will be analyzed and compared with last tested formula of probiotic bacteria carried out by specialized companies, leaders in the world. . Activities and responsibilities of each participant partner:
Activities/parteners Responsabilities Phase I. Activity. Preliminary studies and research on probiotic microorganisms used in the manufacture of functional foods -CO CCAI Description of morphological and functional aspects of probiotics bacteria P1 –UNIV. GALATI Characterization probiotic microflora P2-UNIV. SAPIENTIA Probiotic bacteria action in the intestinal tractus Phase II II. Activity. Research on establishing protective methods for the lactic probiotic bacteria using microencapsulation and ultrasound techniques CO CCAI Elaboration of hipothesis and experimentation of techniques of bacteria protection through clasical microencapsulation and ultrasound P1 –UNIV. GALATI Experimenting the effect of protective techinques of lactic bacteria on the biological activity and characterisation of the used techiniques P2-UNIV. SAPIENTIA Methods of stimulating the developement of lactic bacteria; caracterisation of the resulting biomixtures P3 SC LACTIS SRL Lab testing of the resulting lactic bacteria microcapsules Phase III.Activity. Simulating an experimental model of the digestive tractus for studying the „in vitro” behavior of the microencapsulated probiotic bacteria and comparative studies CO CCAI Realizing and experimentic the simulated functional models; comparative analysis of the results P1 –UNIV. GALATI „In vitro” reproduction of the proximal segment of the digestive tractus. Characteristics and conditions P2-UNIV. SAPIENTIA „In vitro” reproduction of the distal segment of the digestive tractus. Characteristics and conditions Phase IV. Activity. Laboratory drafting of technology of using entrapped probiotic bacteria. Characterization of the obtained product CO CCAI Drafting the technologies using the new biomixtures. Comparative study P3 SC LACTIS SRL Comparative experimenting of clasical and new technologies; product characterisation Phase V. Activity. Darwing up technico-economical studies -CO CCAI Necesity study and technical data providing P3 SC LACTIS SRL Fezability study, study market Phase VI 2010 VI.Activity. Pilot level experiment of the technologies of manufacturing lactic probiotic products using the new biomixtures; clinical trials; drafting technical papers; spreading out results. -CO CCAI Trial level technology elaboration; organizing and supervising clinical trials; functional product characterisation. Patent and/or publishing results documentation P1 UNIV. GALATI Establishing condition for increasing food safety level; Publishing, conferences, documentation, for publishing and/patent of the results P2 UNIV. SAPIENTIA Documentation for publishing and/or patenting results P3 SC LACTIS SRL Testing technologies; realization and characterization of physical, chemical and microbiological products. Description of various events conducted under the project: - Periodic meetings of the partners, at least once / 3 months - Papers presented in specialty newsletters: " Probiotic bacteria microencapsulation.General. Structure microcapsules"
Authors: Ciric Alexandru, Costin, GM - newsletters for Dairy Industry, no. 4, volume 22, trim. IV in 2007, Academic Publishing;
- Participation in International Symposium in Vienna with the theme "Drying & Formulation for Applications in Biotechnology, Feed & Food
Date: 16-17 April 2008;
- Participation Symposium "Partnerships in priority areas - Elements of monitoring of projects funded for areas 4, 5 and 6”, Sinaia, 15-18 April 2008; - Participation in the Symposium "Chemistry and Colloids areas" (IX Symposium of Galati 29-30 May 2008) with the presentation of the papers "Techniques used for encapsulation of probiotic bacteria"; author: Alexander Ciric; -
Participation in the Symposium organized by the University of „DUNAREA DE JOS” of Galati on "Functional Foods: Research on increasing the quality and safety of food through the design, manufacture and launching of new products synbiotic - CALISIN (5-6 June 2008)
The works presented:
Component consortium:
I. University of „Dunarea de Jos” of Galati II. Sapientia Foundation - Sapientia University of Cluj-Napoca The project budget :
Total budget: 2 501 410 lei, of: 2 000 000 from the state budget and 501 410 co-financing Copyright © 2009 CCAI SA, Bucuresti, Romania, all rights reserved |
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